Injectable Drug Compatibility News

In this supplement we added new stability information for the existing drug monograph for TENECTEPLASE. In addition, new compatibility information is reported for these existing monographs:  MORPHINE SULFATE, ROPIVACAINE HYDROCHLORIDE, and ZICONOTIDE; COLISTIMETHATE SODIUM WITH ERTAPENEM, IMIPENEM-CILASTATIN SODIUM, LINEZOLID, MEROPENEM, PIPERACILLIN AND TAZOBACTAM, and VANCOMYCIN HYDROCHLORIDE; and ISAVUCONAZONIUM SULFATE with 95 other drugs.

In this supplement we added new stability information for these existing drug monographs: ALPROSTADIL, METHOTREXATE, and SILDENAFIL CITRATE. In addition, new compatibility information is reported for over 100 existing drug monographs, including entries for CEFTOLOZANE and TAZOBACTAM with 95 other drugs, CEFTAZIDIME AND AVIBACTAM, DOPAMINE HYDROCHLORIDE, HEPARIN SODIUM, PIPERACILLIN AND TAZOBACTAM, SILDENAFIL CITRATE, and VANCOMYCIN HYDROCHLORIDE.

In this supplement we added new stability information for these existing drug monographs: BUSULFAN, CARBOPLATIN, CISPLATIN, CLADRIBINE, CYTARABINE, DACARBAZINE, DACTINOMYCIN, DOPAMINE HYDROCHLORIDE, EPINEPHRINE HYDROCHLORIDE, HYDROCORTISONE SODIUM PHOSPHATE, IDARUBICIN HYDROCHLORIDE, IFOSFAMIDE, METHOTREXATE, MITOMYCIN, MITOXANTRONE HYDROCHLORIDE, NALOXONE HYDROCHLORIDE, PENTOSTATIN, TOPOTECAN HYDROCHLORIDE, VINBLASTINE SULFATE, VINCRISTINE SULFATE, and VINORELBINE TARTRATE. In addition new compatibility information is reported for over 40 existing drug monographs, including entries for PIPERACILLIN AND TAZOBACTAM with VANCOMYCIN HYDROCHLORIDE, ABCIXIMAB with six other drugs, CLONAZEPAM with six other drugs, HALOPERIDOL LACTATE with thirteen other drugs, OMEPRAZOLE HYDROCHLORIDE with five other drugs, and TIROFIBAN HYDROCHLORIDE with seven other drugs.

In this supplement we added new drug monographs with stability and compatibility data for these drugs: BLINATUMOMAB, BRIVARACETAM, ERIBULIN MESYLATE, FERRIC CARBOXYMALTOSE, DECITABINE, FOMEPIZOLE, GLOBULIN, IMMUNE (HUMAN) AND HYALURONIDASE, IBANDRONATE SODIUM, IDARUCIZUMAB, ISAVUCONAZONIUM SULFATE, RASBURICASE, SODIUM FERRIC GLUCONATE COMPLEX, SODIUM FERRIC GLUCONATE COMPLEX IN SUCROSE, SODIUM NITRITE, TEMOZOLOMIDE, VINCRISTINE SULFATE LIPOSOME, and ZOLEDRONIC ACID. Also, we added new stability information for these existing drug monographs: AZTREONAM, BACLOFEN, BUSULFAN, CARBOPLATIN, CEFPIROME SULFATE, CEFEPIME HYDROCHLORIDE, CEFTAZIDIME, DORIPENEM, FENTANYL CITRATE, HEPARIN SODIUM, HETASTARCH, KETAMINE HYDROCHLORIDE, LEVETIRACETAM, MEROPENEM, NITROPRUSSIDE SODIUM, PACLITAXEL, PIPERACILLIN AND TAZOBACTAM, PIPERACILLIN SODIUM, TACROLIMUS, TRANEXAMIC ACID, and VANCOMYCIN HYDROCHLORIDE. In addition...

In this update we added new drug monographs for CEFTAZIDIME AND AVIBACTAM, CEFTOLOZANE AND TAZOBACTAM, and SUGAMMADEX. Also, we added new stability information for these drugs:  AMPICILLIN SODIUM, LABETALOL HYDROCHLORIDE, PIPERACILLIN AND TAZOBACTAM, POLYMYXIN B SULFATE, and PROPAFENONE HYDROCHLORIDE. In addition new compatibility information is reported for ESMOLOL HYDROCHLORIDE, LABETALOL HYDROCHLORIDE, and METOPROLOL HYDROCHLORIDE, each in combination with 14 different drugs. Overall, new compatibility information is included for over 90 unique drug pairs in this supplement.